Amino & PerformanceNo.055

5-HTP

Mood and sleep (serotonin precursor).

Typical / RDA50–200 mg
Upper limitUse with care
EvidenceLimited

How to take it

Timing EveningFood Empty-ishForm 5-hydroxytryptophan

What to know

A serotonin precursor taken for mood and sleep. The real concern is safety, not just efficacy: combining it with serotonergic drugs can be dangerous.

Interactions & cautions

  • Do NOT combine with antidepressants (SSRIs) — serotonin syndrome risk.

Do you actually need it?

Skip if on antidepressants. Discuss with a doctor first.

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Reference values: NIH Office of Dietary Supplements, adult general population. Educational information only — not medical advice. Confirm with a healthcare professional.

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